Sunday, February 24, 2019
DNA the Master Code for All Living Things
Bacteria, zebras, mosquitoes, anacondas, essentially all living things have angiotensin converting enzyme thing in common which serves them what they argon. It is deoxyribonucleic blistering. It is one of the superlative biological discoveries in the history of mankind. It is not only related to biology but is tied(p) to the study of chemistry as well be set of the convoluted molecular organize. desoxyribonucleic acid is short for the whit deoxyribonucleic acid. RNA or ribonucleic acid is an new(prenominal) nucleic acid derived from desoxyribonucleic acid and accustomd as a template to sword proteins, the reaping of the genic code.In an article, What is deoxyribonucleic acid? written by throng Randerson, desoxyribonucleic acid is described as, he master code for life the instruction nurse that each organismnessness uses to run its body and govern its behavior, a have got that each creature hands on to its offspring, either in lavish or in part. In other words i t describes how at time not the whole book (desoxyribonucleic acid) is passed down from p arnt to progeny. A overprotect and mother both contribute their deoxyribonucleic acid making the son convertible but not identical to his father and mother. Also, because desoxyribonucleic acid stores all genetic data including dioceanses, which can be passed down from generation to generation. These diseases atomic number 18 the incumbrance of a mutation in the DNA structure.In 1868, a Swiss physician and biologist extracted a phosphorus containing substance. He called it nuclein because he gear up it in the nuclei of several kiosks. He managed to extract this substance from discarded surgical bandages, specifically by examining the pus cells (pus cells are white blood cells). jam Watson, an American geneticist, and Francis Crick, a British physicist studying in the University of Cambridge, began examining x-ray images do by Rosalind Franklin and Maurice Wilkins. In 1953, James and Francis constructed the first three-dimensional model of the DNA structure.The model showed all nitrogen-bearing bases, pentoses (sugar), and orthophosphate groups. Several years later, James Watson, Francis Crick, and Maurice Wilkins received the Nobel Prize for Physiology or Medicine. Before the three-dimensional model, Erwin Chargaff discovered a pattern between the base agrees. He discovered that the amount of type A is the same amount of thymine. the same is true for the other base braces guanine and cytosine. Chargaffs disco rattling led him to understand the basic wedlock rules. You might wonder what makes our DNA divers(prenominal) from the DNA of a sheep, sea urchin, or a turtle.Based on the studies of Chargaff and the rest of his colleagues at capital of South Carolina University, the four nitrogenous bases occur in diverse ratios in the DNAs of different organisms and that the bases have a numerical relationship. For modeling, The base composition (mol percentage ) of Homo sapiens is 30. 9 % adenine, 19. 9% guanine, 19. 8% cytosine, and 29. 4% thymine. This shows that Chargaffs study was very helpful for James Watson and Francis Cricks three-dimensional model of a DNA molecule. I chose to research DNA because it is a very provoke topic to discuss.It makes me who I am, my hair, eye, and skin color, my height and weight, overall health, metabolism, etc. I find both biology and chemistry my favorite subjects and DNA because it is a key molecuel that defines health. In the future I plan to become a M. D. (Medical Doctor). I will definitely have to be familiar with this molecule and what DNA sequences mean in case I needed to advert a patient with a certain genetic disease. By examining his or her genetic code I could determine possible diseases. I actually enjoy whatever type of problem solving. I could utilize this experience to explore disease in my own family, specifically my dads stead.From my grandfather to my own father and uncles, e veryone has minor cardiovascular diseases caused by high-pitched cholesterol. I want to discover what mutation in my familys DNA that causes this condition and develop treatments to improve their health. DNA molecules are located in the nucleus of a cell. When they are tightly packed together they are known as chromosomes. The structure of DNA is very complicated. DNA is a echo helix molecule. The structure looks deal a twisted play. A double helix is the molecular structure created from double-stranded molecules of nucleic acids held together by hy drogen hold fast between nucleotides.Nucleotides contain three characteristic components (1) a nitrogenous base, (2) a pentose (sugar), and (3) phosphate group. Four nitrogenous bases make up DNAs support of the double helix adenine (A), guanine (G), cytosine (C), and thymine (T). These bases are shatter into two groups. (A) and (G) are in the purine base group and (C) and (T) are in the pyrimidine base groups. In the structure of DNA base pairs are make between the four bases. A base pair is when two nitrogenous bases (a purine to a pyrimidine or vice versa) are linked by feeble hydrogen bonds.Adenine (A) and thymine (T) form a base pair and guanine (G) and cytosine C) form a base pair. In the structure of DNA (A) and (T) are held together by two hydrogen bonds, epoch (C) and (G) are held together by three hydrogen bonds. The next components of DNA form the backbone of the two spiraling strands. The backbones consist of alternating phosphate and pentose (sugar). Two kinds of pentoses are found in nucleic acids, deoxyribose and ribose. Deoxyribose is basically the same as ribose but it has one less oxygen atom in its structure. The phosphate group is machine-accessible to the pentose (deoxyribose or ribose) on the backbone of the DNA structure.They are both held together by covalent bonds. The pentose is in any case connected to the nitrogenous base. When a pentose (sugar) and a base combine it is called a nucleoside. An example of a nucleoside, is when the base thymine bonds with the pentose (sugar) deoxyribose, deoxythymidine forms. The nucleoside then combines with the phosphate to make the nucleoside a nucleotide. In the article How DNA Works, Craig Freudenrich explains how the hydrogen bonds between phosphates cause the DNA strand to twist.The nitrogenous bases point inward on the ladder and form pairs with bases on the other side. This makes DNA look somewhat equal a spiraling staircase. DNA functions to store the complete genetic information required to specify the structure of all the proteins of each species of organism, to program in time and space the orderly biosynthesis (the process of converting simple nutrients like sugars, lipids, and amino acids into complex products like, proteins and vitamins) that make cell and tissue, and organs which determine the activities of an organism throughout its life cycle, and determine the distinctiveness of the given organism.DNA also has another function. It is meant to be replicated so copies can be passed down from cell to cell and generation to generation. The National Human Genome Research Institute describes the impartation occurs In familiar reproduction, organisms inherit half of their nuclear DNA from the mannish parent and half from the female parent. However, organisms inherit all of their mitochondrial DNA from the mother. This occurs because only egg cells, and not sperm cells, keep their mitochondria during fertilization.To complete these instructions, DNA sequences are transcribed into messages made of RNA and ultimately translated into sequences of amino acids to produce proteins. DNA genetic information is composed of specific long sequences of A, T, G, and C. The process begins with the sequences being transferred to a single strand RNA molecule. RNA is only jolly different from DNA. The important difference between them is that one of the pyrimidine bases are not the same. Thymine is a principal pyrimidine in DNA, while uracil is a principal pyrimidine in RNA.The new RNA (mRNA) molecule is a courier containing transcribed code from the DNA molecule. The mRNA travels out of the nucleus into the cytoplasm. check to The National Human Genome Research Institute, in the cytoplasm the information contained in the mRNA molecule is translated into the wrangle of amino acids, which are the building blocks of proteins. This language tells the cells protein-making machinery the precise order in which to link the amino acids to produce a specific protein.This is a major task because there are 20 types of amino acids, which can be placed in many different orders to form a wide variety of proteins. Proteins do most of the clobber in our bodies they move molecules in our bodies, they help us move by making our muscles, they help create our immune system that helps protect from any infections in our body or illnesses, and much more. DNA is one of the greatest discoveries my man. It was not discovered by a single human being but several. DNA is what makes a female human to give stimulate to a baby girl not to a baby giraffe or cub.DNA is passed down from generation to generation by sexual reproduction. Half of the fathers genes and half of the mothers go to their son or daughter. Your DNA is not the same as your cronys because sometimes you get more from your moms side or more from your dads side, it all depends. It is extraordinary how we are made from a string of DNA molecules that construct our body and make us who we are. DNA is now at a point where we use it for many reasons, not just for research. DNA forensics is one of the most virtual(a) ways of using DNA.Forensics is the application of many sciences to discover aspects about a annoyance. A government website describing DNA forensics, lists many examples of DNA uses for Forensic Identification. They allow identification of potential suspects whose DNA whitethorn match evidence go forth at crime scenes exoneration of persons wrongly accused of crimes identification of crime and catastrophe victims establishment of paternity and other family relationships identification of endangered and saved species as an aid to wildlife officials (could be used for prosecuting poachers) detection of acteria and other organisms that may pollute air, water, soil, and food Matching organ donors with recipients in transplant programs determination of pedigree for seed or livestock breeds and authentication of consumables such as caviar and wine. It is great that DNA has been incorporated into forensics. Hopefully, in the near future, DNA technologies will be incorporated in a variety of other applications.
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